There was no evidence of fibrosis around the cysts. In two cases, surgical excision was performed. In three (27%) cases, no response was obtained (2 cases) or the lymphangioma recurred (1 case) after two to three injections. Eight (73%) patients had complete or subcomplete resolution of the lymphangioma after one or two injections. ![]() They were followed up for a period of 5 to 68 (mean 30) months. Children were injected under sedation.Results: Eleven patients were treated with injections of OK-432: 7 children and 4 adults. All injections were performed under ultrasound guidance. Objective: To describe our experience with sclerosing treatment of lymphangiomas in the head and neck region by intralesional injections of OK-432.Study Design: Case series.Methods: Patients with the diagnosis of a macrocystic-type cervical lymphangioma were treated by one to three intralesional injections of OK-432 (0.01 mg of OK-432/1 mL of lymphangioma fluid, up to a maximum of 0.2 mg in the first injection and 0.3 mg in the second or third injections).
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